Of uncertain origin; an adder or other poisonous snake (literally or figuratively) -- viper.
Thayer's Greek Lexicon
Strong's 2191: ἔχιδνα
ἔχιδνα, ἐχιδνης, ἡ, a viper: Acts 28:3 (Hesiod, Herodotus, Tragg., Aristophanes, Plato, others); γεννήματαἐχιδνῶνoffspring of vipers (anguigenae, Ovid, metam. 3,531), addressed to cunning, malignant, wicked men: Matthew 3:7; Matthew 12:34; Matthew 23:33; Luke 3:7.
Matthew 3:7 - N-GFP GRK:αὐτοῖς Γεννήματα ἐχιδνῶν τίς ὑπέδειξεν NAS: to them, You brood of vipers, who KJV: O generation of vipers, who INT: to them Brood of vipers who forewarned
Matthew 12:34 - N-GFP GRK:γεννήματα ἐχιδνῶν πῶς δύνασθε NAS: You brood of vipers, how can KJV: O generation of vipers, how can ye, INT: Offspring of vipers how are you able
Matthew 23:33 - N-GFP GRK:ὄφεις γεννήματα ἐχιδνῶν πῶς φύγητε NAS: you brood of vipers, how KJV: [ye] generation of vipers, how INT: [You] serpents offspring of vipers how shall you escape
Luke 3:7 - N-GFP GRK:αὐτοῦ Γεννήματα ἐχιδνῶν τίς ὑπέδειξεν NAS: by him, You brood of vipers, who KJV: O generation of vipers, who INT: him Offspring of vipers who forwarned
Acts 28:3 - N-NFS GRK:τὴν πυράν ἔχιδνα ἀπὸ τῆς NAS: them on the fire, a viper came KJV: there came a viper out of INT: the fire a viper out of the