With such a hope as this, we speak with all plainness;
Seeing then that we have such hope, we use great plainness of speech:
Since we have such [glorious] hope (such joyful and confident expectation), we speak very freely and openly and fearlessly.
Having therefore such a hope, we use great boldness of speech,
So, since we have such a hope, we act with great confidence.
Therefore, having such a hope, we act with much confidence,